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In reply

We thank Oremus and Oremus for their comments on our recent article.¹ Based on the NHANES 1999-2000 findings, we concur that the difference in blood pressure control between African American and white populations is present for men and not for women. Men were the focus of our report. Their letter sites evidence that genetic factors are a determinant of the blood pressure response to antihypertensive medications. Some published studies are consonant with this view. Nevertheless, because the populations at the VA and non-VA site were derived from the same geographic communities, it seems improbable that genetic differences between African American men at VA and non-VA sites explains the higher control rate for those receiving care at the VA.

The commentary also indicates that ethnicity influences blood pressure responses to antihypertensive medications. As reported, our analysis indicated that the better BP control rate among African American men receiving care . . . [Full Text of this Article]

AUTHOR INFORMATION
Shakaib U. Rehman, MD; Florence N. Hutchison, MD; Eni C. Okonofua, MD, MSCR; Brent M. Egan, MD

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