This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on ISI (2)  • Contact me when this article is cited  Related Content  • Related letter  • Related article  • Similar articles in this journal  Topic Collections  • Cardiovascular Disease/ Myocardial Infarction  • Hematology, Other  • Alert me on articles by topic

Arch Intern Med. 2005;165:487-488.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Studies of inflammation status in relation to vascular outcomes, using diagnostic tests ranging from leukocyte count determination to assessment of C-reactive protein (CRP) concentration, cellular adhesion molecules, and markers of plaque stability have progressed in recent years. Most recent attention has been on CRP; concentrations in the top third of the population are associated with an increased risk of approximately 50% for first future coronary and stroke events.¹

In this issue of the ARCHIVES, Margolis and colleagues² from the Women’s Health Initiative (WHI) Research Group report that a higher leukocyte count is associated with an increased risk of cardiovascular events and mortality among 66 261 women at 40 centers followed in the WHI Observational Study. Study participants were primarily those who inquired but were not eligible, or did not desire, to participate in the WHI clinical trials of hormone therapy and dietary intervention. The major finding of the study . . . [Full Text of this Article]

CONSIDERATIONS FOR CLINICAL APPLICATION


LEUKOCYTE COUNT AND OTHER INFLAMMATION FACTORS

AUTHOR INFORMATION
Mary Cushman, MD, MSc

RELATED LETTER

Leukocyte Response to Dental Plaque Accumulation: A Risk Factor for Heart Disease?
Michael J. Kowolik and Sherie A. Dowsett
Arch Intern Med. 2005;165(15):1795-1796.
EXTRACT | FULL TEXT  

RELATED ARTICLE

Leukocyte Count as a Predictor of Cardiovascular Events and Mortality in Postmenopausal Women: The Women’s Health Initiative Observational Study
Karen L. Margolis, JoAnn E. Manson, Philip Greenland, Rebecca J. Rodabough, Paul F. Bray, Monika Safford, Richard H. Grimm, Jr, Barbara V. Howard, Annlouise R. Assaf, Ross Prentice, and for the Women’s Health Initiative Research Group
Arch Intern Med. 2005;165(5):500-508.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

The Leukocyte Count, A Measure and Predictor of Coronary Events
Futterman and Lemberg
Am J Crit Care 2007;16:401-404.
FULL TEXT  

Leukocyte Response to Dental Plaque Accumulation: A Risk Factor for Heart Disease?
Kowolik and Dowsett
Arch Intern Med 2005;165:1795-1796.
FULL TEXT  

WBC Count Predicts CV Events in Postmenopausal Women
Journal Watch Cardiology 2005;2005:7-7.
FULL TEXT