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  Vol. 165 No. 7, April 11, 2005 TABLE OF CONTENTS
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Nickel and Sulfites Food Allergy in Patients With Angioedema Associated With ACE Inhibitor Use

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Cicardi et al1 concluded that stopping angiotensin-converting enzyme (ACE) inhibitor use without further assessment is a successful measure in most patients who develop angioedema while taking this drug. We investigated the frequency of food allergy and sensitization to some food additives and contaminants in a group of 21 hypertensive patients referred for angioedema, urticaria, and/or itching while receiving ACE inhibitor therapy. Nine patients had angioedema, 4 patients had urticaria and/or angioedema, and 8 patients had itching. The median length of follow-up was 22.5 months (range, 4-44 months). Withdrawing the ACE inhibitor resulted in complete disappearance of symptoms in 18 patients (86%).

Prick testing with common allergens was performed for screening of type I allergies. Patients were patch tested with the European standard series and with selected food additives including sulfites (sodium bisulfite and potassium metabisulfite) and benzoates. Of the 21 patients tested, 17 (81%) exhibited at least 1 positive reaction . . . [Full Text of this Article]


AUTHOR INFORMATION
Sergio De Marchi, MD; Laura Perale, MD; Emanuela Cecchin, MD; Leonardo Alberto Sechi, MD



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