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We refer to a recent publication¹ and comment² on the lack of association between insulin resistance and plasma triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C) levels and the TG/HDL-C ratio in African Americans. To add some information in a non-American population, we present data from the Seychelles (Indian Ocean), where most of the population is of African descent. We assessed cardiovascular risk factors, including fasting blood markers, in a representative sample of the population aged 25 to 64 years.³ We calculated homeostasis model assessment of insulin resistance (HOMA-IR)⁴ as

Fasting Serum Insulin Level (µU/mL) x Fasting Blood Glucose Level (mmol/L)/22.5.

Participants were categorized as "African," "mixed," or "non-African" (white, Indian, or Chinese) based on morphological criteria. Results presented herein are based on nondiabetic individuals who are overweight (body mass index [calculated as weight in kilograms divided by the square of height in meters] 25). Insulin resistance was defined within each . . . [Full Text of this Article]

AUTHOR INFORMATION
Pascal Bovet, MD, MPH; David Faeh, MD; Anne Gabriel, MD; Luc Tappy, MD

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