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Adverse drug reactions (ADRs) frequently occur in hospitalized elderly patients.¹ In geriatric medicine it is common practice to evaluate pharmacotherapy during hospitalization, often leading to interventions in general and interventions related to ADRs in specific. After discharge, the general practitioner (GP) takes over responsibility for the pharmacotherapeutic management of the patient. This requires adequate transfer of information to primary care about these interventions and the reasons for it. The objective of this study was to measure the rate of represcription of drug therapies discontinued because of an ADR.

Methods

We studied consecutively hospitalized patients on geriatric wards of the University Medical Center in Utrecht (n = 105) and of the Tweesteden teaching hospital in Tilburg (n = 110), the Netherlands. Their mean age was 82 years (range, 59-96 years), and 67% were female.

Adverse drug reactions identified by the attending physician were extracted from medical files by 2 of the investigators (C.M.J.v.d.L. and M.C.H.K.).

Causality . . . [Full Text of this Article]

Results

Comment

AUTHOR INFORMATION
Carolien M. J. van der Linden, MD; Marieke C. H. Kerskes, PharmD; Annemarie M. H. Bijl, MD; Huub A. A. M. Maas, MD; Antoine C. G. Egberts, PharmD, PhD; Paul A. F. Jansen, MD, PhD

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