 |
|
New-Onset Diabetes Mellitus Less Deadly Than Elevated Blood Pressure?
Following the Evidence in the Administration of Thiazide Diuretics
Arch Intern Med. 2006;166:2174-2176.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
The day a physician loses his humility is the day that physician becomes a menace to society.—Richard Gorlin, MD
The primary outcome analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)1 demonstrated that first-step therapy with a thiazide diuretic was equally effective in reducing major cardiovascular events compared with either a calcium channel blocker (CCB) or angiotensin-converting enzyme (ACE) inhibitor. The results did not bring joy to the pharmaceutical industry, academicians with excessively close ties to the industry, or hypertension specialists wedded to the importance of renin-angiotensin system blockade. The report from the ALLHAT trial in this issue of the ARCHIVES2 will not bring solace to any of these groups. In this retrospective analysis, ALLHAT investigators demonstrate that patients with hypertension who develop diabetes mellitus (DM) while taking thiazide fare better than those who develop DM undergoing treatment with a CCB or ACE inhibitor. . . . [Full Text of this Article]
AUTHOR INFORMATION
Robert A. Phillips, MD, PhD
RELATED ARTICLE
Fasting Glucose Levels and Incident Diabetes Mellitus in Older Nondiabetic Adults Randomized to Receive 3 Different Classes of Antihypertensive Treatment: A Report From the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
Joshua I. Barzilay, Barry R. Davis, Jeffrey A. Cutler, Sara L. Pressel, Paul K. Whelton, Jan Basile, Karen L. Margolis, Stephen T. Ong, Laurie S. Sadler, John Summerson, and for the ALLHAT Collaborative Research Group
Arch Intern Med. 2006;166(20):2191-2201.
ABSTRACT
| FULL TEXT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Thiazide-Induced Dysglycemia: Call for Research From a Working Group From the National Heart, Lung, and Blood Institute
Carter et al.
Hypertension 2008;52:30-36.
FULL TEXT
What If Chlorthalidone-Associated Hyperglycemia Develops?
Silver
Arch Intern Med 2007;167:1434-1434.
FULL TEXT
|
