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Preventing Cognitive Decline in Usual Aging
Arch Intern Med. 2006;166:2433-2434.
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Cognitive decline in later life is undoubtedly a complex process involving many underlying mechanisms. In some instances, mild impairment will represent a way station along the descending road to frank dementia. In many others, it will be a signpost for the uneven path of "usual" aging, not necessarily a pleasant passage, but a route conceptually closer to the age-associated declines in respiratory vital capacity and maximum heart rate than to a defined illness such as Alzheimer disease. As baby boomers age and the oldest segment of the population continues to grow, it becomes increasingly urgent to develop strategies for the delay, prevention, or amelioration of age-associated cognitive decline.
In considering cognitive interventions, it is useful to distinguish 3 broad target groups. The first consists of patients with specific forms of dementia (eg, Alzheimer disease, frontotemporal dementia, and vascular dementia). The second consists of patients with "mild cognitive impairment,"1 conceptualized in . . . [Full Text of this Article]
AUTHOR INFORMATION
Mark A. Espeland, PhD;
Victor W. Henderson, MD, MS
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