This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (6)  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in this journal  Topic Collections  • Cardiovascular System  • Renal Diseases, Other  • Cardiovascular Disease/ Myocardial Infarction  • Alert me on articles by topic  Social Bookmarking   What's this?

Cause and Consequence of Cardiovascular Disease

Barry I. Freedman, MD; Thomas D. DuBose Jr, MD

Arch Intern Med. 2007;167(11):1113-1115.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The widely held view that albuminuria and/or reduced glomerular filtration rate (GFR) inexorably progress to end-stage renal disease (ESRD) requiring kidney replacement therapy is not uniformly accurate. Inadequately treated nephropathy risk factors in those with chronic kidney disease (CKD) such as hyperglycemia, hypertension, and proteinuria often lead to declining kidney function. However, the number of individuals at risk for ESRD by virtue of having CKD demonstrates that only a minority reach ESRD.¹ Indeed, most will ultimately die of cardiovascular disease (CVD) before needing renal replacement therapy.²

There are currently about 387 000 patients in the United States and 1.8 million worldwide who require dialysis therapy or kidney transplantation for survival.^{1, 3} Among the 100 000 patients with incident ESRD in the United States each year, 42% have diabetic nephropathy, more than 90% from type 2 diabetes mellitus.¹ The US health care system has not . . . [Full Text of this Article]

AUTHOR INFORMATION


CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLES

Independent Components of Chronic Kidney Disease as a Cardiovascular Risk State: Results From the Kidney Early Evaluation Program (KEEP)
Peter A. McCullough, Claudine T. Jurkovitz, Pablo E. Pergola, Janet B. McGill, Wendy W. Brown, Alan J. Collins, Shu-Cheng Chen, Suying Li, Ajay Singh, Keith C. Norris, Michael J. Klag, George L. Bakris, and for the KEEP Investigators
Arch Intern Med. 2007;167(11):1122-1129.
ABSTRACT | FULL TEXT  

Cardiovascular Disease and Subsequent Kidney Disease
Essam F. Elsayed, Hocine Tighiouart, John Griffith, Tobias Kurth, Andrew S. Levey, Deeb Salem, Mark J. Sarnak, and Daniel E. Weiner
Arch Intern Med. 2007;167(11):1130-1136.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Cardiovascular disease in chronic kidney disease
Saran and DuBose
Ther Adv Cardiovasc Dis 2008;2:425-434.
ABSTRACT  

CKD Increases the Risk of Age-Related Macular Degeneration
Liew et al.
J. Am. Soc. Nephrol. 2008;19:806-811.
ABSTRACT | FULL TEXT