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  Vol. 167 No. 14, July 23, 2007 TABLE OF CONTENTS
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COMMENTS & OPINIONS
C-Reactive Protein Is Still a Potential Aid in Rheumatoid Arthritis Predictors—Reply

Nancy A. Shadick, MD, MPH; Elizabeth W. Karlson, MD; I-Min Lee, MBBS, ScD

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In reply

Tanzer raises 2 issues for discussion related to potential confounders in our study examining the association of CRP level with the risk of developing RA.1 First, as he indicates, smoking is a known risk factor for incident RA. In our cohort, 38% of RA cases were never smokers and 52% were past smokers at the time of diagnosis vs 52% and 37%, respectively, among women who did not develop RA. In our analyses, we adjusted for smoking status; thus, our findings were unlikely to reflect confounding by smoking. Second, regarding statin use, the blood samples in our study were collected between 1993 and 1995, a period when the prevalence of statin use was relatively low. We did not have data on statin use at baseline to adjust for this; however, there was unlikely to be . . . [Full Text of this Article]


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RELATED LETTER

C-Reactive Protein Is Still a Potential Aid in Rheumatoid Arthritis Predictors
Jerome Tanzer
Arch Intern Med. 2007;167(14):1552.
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