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COMMENTS AND OPINIONS
Nonspecific Troponin Elevation
Faisal Latif, MD
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Alcalai et al1 report a very well designed study on the significance of troponin elevation in hospitalized patients. However, the authors have coined a new term, nonthrombotic troponin elevation (NTTE). This term categorically implies an absence of thrombus in the coronary circulation. Coronary angiography was performed on only some of the patients in this group among whom no significant coronary lesions were found. Without performing a randomized study in which coronary angiography is performed in all of these patients, it cannot be absolutely confirmed that these patients did not have any plaque rupture in the coronary circulation. This could even represent the final cause of death in patients who have sepsis or renal failure. Particularly, in an era in which late thrombosis of drug-eluting stents has emerged as a major issue, this becomes ever more important. Development of thrombosis in a preexisting stent can be . . . [Full Text of this Article] AUTHOR INFORMATION
RELATED LETTER
Nonspecific Troponin Elevation—Reply
Ronny Alcalai, David Planer, Arthur Pollak, and Chaim Lotan
Arch Intern Med. 2007;167(17):1907.
EXTRACT
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RELATED ARTICLE
Acute Coronary Syndrome vs Nonspecific Troponin Elevation: Clinical Predictors and Survival Analysis
Ronny Alcalai, David Planer, Afsin Culhaoglu, Aydin Osman, Arthur Pollak, and Chaim Lotan
Arch Intern Med. 2007;167(3):276-281.
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