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COMMENTS AND OPINIONS
Migraine and Heart Rate Variability
Antonio Perciaccante, MD;
Alessandra Fiorentini, MD;
Rosita Valente;
Massimo Granata, MD;
Luigi Tubani, MD
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We read with interest the article by Kurth et al1 on the association between migraine and increased risk of CVD in men. In a previous study, the authors have reported an association among active migraine with aura and increased risk of CVD, CHD, and ischemic stroke in women.2 The biological link between migraine and CVD and CHD is complex and currently unclear. Several mechanisms may be involved such as prothrombotic and vasoactive factors.
We report preliminary data from our study showing the presence of cardiac autonomic dysfunction in subjects with migraine. A total of 28 subjects (18 women and 10 men; mean ± SD age, 36 ± 4.2 years) with active migraine with aura, diagnosed according to criteria of the International Headache Society, were enrolled. All subjects were normotensive and normal weight and without metabolic, endocrine, cardiovascular, and renal diseases, . . . [Full Text of this Article]
AUTHOR INFORMATION
RELATED LETTER
Migraine and Heart Rate Variability—Reply
Tobias Kurth, J. Michael Gaziano, Nancy R. Cook, Vadim Bubes, Giancarlo Logroscino, Hans-Christoph Diener, and Julie E. Buring
Arch Intern Med. 2007;167(20):2264-2265.
EXTRACT
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RELATED ARTICLE
Migraine and Risk of Cardiovascular Disease in Men
Tobias Kurth, J. Michael Gaziano, Nancy R. Cook, Vadim Bubes, Giancarlo Logroscino, Hans-Christoph Diener, and Julie E. Buring
Arch Intern Med. 2007;167(8):795-801.
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