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Gijsbertus Ziere, MD; Jeanne P. Dieleman, PhD; Tischa J. M. van der Cammen, MD, PhD; Bruno H. Ch. Stricker, MB, PhD

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We read with much interest the original investigation by Richards et al.¹ They indicate that daily SSRI use in adults 50 years and older was associated with a 2-fold increased risk of clinical fragility fracture after adjustment for potential covariates. These findings are very interesting, and, as the authors state, may have important public health consequences. However, some comments on this article can be made.

Our first concern pertains to the statistical analysis. It is unclear from the article how many fractures were included in the study. Hence, we cannot judge the validity of the statistical model including numerous covariates. Also, it is not mentioned how the authors dealt with dropout and other types of fracture. Furthermore, a Cox-proportional hazards model can be used when the time to event . . . [Full Text of this Article]

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