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COMMENTS & OPINIONS
High Recurrence Rate of CA-MRSA Skin and Soft Tissue Infections
Daniel J. Skiest, MD;
Travis W. Cooper, PharmD
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We read with interest the study by Shastry et al1 describing community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections (SSTIs) in men who have sex with men. Their study included 100 men with SSTIs due to MRSA; the majority of their cohort was seropositive for human immunodeficiency virus (HIV) (mean CD4 cell count, 497 cells/µL). Shastry et al1 report a high rate of recurrent MRSA SSTIs; 27 of 87 patients (31%) had a recurrence, of which 18 had a recurrence at a new site. Thus, 21% had a recurrence of MRSA SSTI at a new site.
The rate of resolution of the original SSTI is not clear from their study. Did all patients with recurrent SSTI have resolution of the original infection? It would also be of interest to know whether resolution and recurrence of SSTI were affected by receipt . . . [Full Text of this Article]
AUTHOR INFORMATION
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