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COMMENTS & OPINIONS
The Effect of Obesity on Disability vs Mortality in Older American: The Potential Implication of Testosterone—Reply
Soham Al Snih, MD, PhD;
Kenneth J. Ottenbacher, PhD, OTR;
Kyriakos S. Markides, PhD;
Yong-Fang Kuo, PhD;
Karl Eschbach, PhD;
James S. Goodwin, MD
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In reply
We appreciate the comments from Schulman. Unfortunately, the data sets we used did not include information on testosterone levels.
We agree with Dyer that obesity is an epidemic and is associated with serious health problems. Our results show that the adverse impact of obesity in elderly subjects is seen in increasing risk of disability but not in risk of mortality. Our findings of reduced or no association of increased body mass index with subsequent mortality in elderly subjects has been reported in several other longitudinal studies.1-5 All of the studies that Dyer cites focused on populations younger than 65 years.
AUTHOR INFORMATION
Correspondence: Dr Al Snih, Sealy Center on Aging, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555-0460 (soalsnih@utmb.edu).
1. Flegal KM, Graubard BL, Williamson DF, Gail MH. Excess deaths associated with underweight, overweight, and obesity. JAMA. 2005;293(15):1861-1867.
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2. Stevens J, Cai J, Pamuk ER, Williamson DF, Thun MJ, Wood JL. The effect of age on the association between body mass index and mortality. N Engl J Med. 1998;338(1):1-7.
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3. Bender R, Jockel KH, Trautner C, Spraul M, Berger M. Effect of age on excess mortality in obesity. JAMA. 1999;281(16):1498-1504.
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4. Diehr P, Bild DE, Harris TB, Duxbury A, Siscovick D, Rossi M. Body mass index and mortality in nonsmoking older adults: the Cardiovascular Health Study. Am J Public Health. 1998;88(4):623-629.
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5. Grabowski DC, Ellis JE. High body mass index does not predict mortality in older people: analysis of the Longitudinal Study of Aging. J Am Geriatr Soc. 2001;49(7):968-979.
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ISI
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Arch Intern Med. 2007;167(22):2528.
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