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  Vol. 167 No. 8, April 23, 2007 TABLE OF CONTENTS
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RESEARCH LETTERS
Passive Transfer of Peanut Hypersensitivity by Fresh Frozen Plasma

Donald M. Arnold, MD, MSc, FRCPC; Morris A. Blajchman, MD, FRCPC; Julie DiTomasso, MLT, ART; Myron Kulczycki, MLT; Paul K. Keith, MD, MSc, FRCPC

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The passive transfer of clinically important nut allergy by the transfusion of fresh frozen plasma (FFP) has, to our knowledge, never before been documented. We report a case of peanut anaphylaxis in a nonatopic recipient of leukocyte-depleted FFP collected from a peanut-allergic donor.

Report of a Case

In preparation for gastrointestinal endoscopy, a nonatopic 80-year-old woman receiving long-term warfarin therapy was given a transfusion of 2 U of leukoreduced FFP because her preoperative international normalized ratio was 1.3 (normal range, 0.8-1.2). Two days later, she ate a muffin and some peanut butter and, within minutes, developed throat tightness, dyspnea, dysphagia, and a pruritic rash. Her oxygen saturation was 88%. Aerosolized racemic epinephrine and intravenous corticosteroids were administered, and her symptoms resolved within several hours. She had never before had an . . . [Full Text of this Article]


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