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COMMENTS AND OPINIONS
Relationship Between Serum Testosterone and Cardiovascular Risk Profile in the General Population
Martina Montagnana, MD;
Giuseppe Lippi, MD
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Although cardiovascular risk is influenced by sex hormones, the relationship between endogenous testosterone level and cardiovascular risk profile is controversial and mainly based on relatively small groups of individuals.1 Recently, Maggio et al2 concluded that a decline in anabolic hormone levels, especially testosterone, is a strong independent predictor of mortality in men.
With the aim to investigate the relationship between endogenous testosterone levels and cardiovascular risk profile in the general population, we retrospectively analyzed associations between measurements of serum testosterone and fasting plasma glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol to HDL-C ratio, and the atherogenic index of plasma (AIP) obtained from consecutive outpatients referred to our clinical laboratory by general practitioners for blood testing over the past 2 years. Venous blood was routinely collected in the morning from fasting subjects. Fasting plasma glucose, total cholesterol, HDL-C, . . . [Full Text of this Article] AUTHOR INFORMATION
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Marcello Maggio, Fulvio Lauretani, Gian Paolo Ceda, Stefania Bandinelli, Shari M. Ling, E. Jeffrey Metter, Andrea Artoni, Laura Carassale, Anna Cazzato, Graziano Ceresini, Jack M. Guralnik, Shehzad Basaria, Giorgio Valenti, and Luigi Ferrucci
Arch Intern Med. 2007;167(20):2249-2254.
ABSTRACT
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