This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in this journal  Topic Collections  • Lipids and Lipid Disorders  • Metabolic Diseases  • Nutritional and Metabolic Disorders, Other  • Obesity  • Cardiovascular Disease/ Myocardial Infarction  • Diabetes Mellitus  • Alert me on articles by topic

A Tale of 2 Sites

Lewis Landsberg, MD

Arch Intern Med. 2008;168(15):1607-1608.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Epidemiology has taught the profession that clinical medicine entails a probabilistic approach. Inherent in the concept of risk is the realization that not all persons at risk develop disease and that some persons without identifiable risk do. The predictive value of risk factors for disease can, nonetheless, be refined, and such refinement may enhance their usefulness. Cholesterol level is a risk factor for coronary artery disease, but the predictive value is markedly enhanced by fractionating total cholesterol into low-density and high-density lipoprotein components. The same is true for obesity. Two articles in this issue of the Archives (Stefan et al¹ and Wildman et al²) present data that seek to further refine the well-known cardiovascular risk imposed by obesity.

Jean Vague, a French clinician with a large obesity practice, first described an important heterogeneity among his obese patients.³ Writing more than 50 years ago, Vague noted 2 . . . [Full Text of this Article]

AUTHOR INFORMATION

RELATED ARTICLES

Identification and Characterization of Metabolically Benign Obesity in Humans
Norbert Stefan, Konstantinos Kantartzis, Jürgen Machann, Fritz Schick, Claus Thamer, Kilian Rittig, Bernd Balletshofer, Fausto Machicao, Andreas Fritsche, and Hans-Ulrich Häring
Arch Intern Med. 2008;168(15):1609-1616.
ABSTRACT | FULL TEXT  

The Obese Without Cardiometabolic Risk Factor Clustering and the Normal Weight With Cardiometabolic Risk Factor Clustering: Prevalence and Correlates of 2 Phenotypes Among the US Population (NHANES 1999-2004)
Rachel P. Wildman, Paul Muntner, Kristi Reynolds, Aileen P. McGinn, Swapnil Rajpathak, Judith Wylie-Rosett, and MaryFran R. Sowers
Arch Intern Med. 2008;168(15):1617-1624.
ABSTRACT | FULL TEXT