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A New Predictor of Future Hypertension?

Myron H. Weinberger, MD

Arch Intern Med. 2008;168(16):1732.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Cold exposure is known to raise blood pressure (BP). Long ago, a systematic evaluation of this effect resulted in the "cold pressor" test (CPT), in which the nondominant arm was immersed to the wrist in ice water for 90 to 120 seconds and the rise in BP was measured in the opposite arm. Most students of medicine and physiology can personally recall serving as experimental subjects in the laboratory during this somewhat painful procedure. The rise in BP is mediated primarily by activation of the sympathetic nervous system, and the magnitude and duration of increase has been shown to be influenced by a variety of factors, among them basal BP levels.

In this issue of the Archives, Chen et al,¹ participating in the GenSalt (Genetic Epidemiology Network of Salt Sensitivity) study, report on the effects of the CPT in a large group of rural Chinese . . . [Full Text of this Article]

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Association Between Blood Pressure Responses to the Cold Pressor Test and Dietary Sodium Intervention in a Chinese Population
Jing Chen, Dongfeng Gu, Cashell E. Jaquish, Chung-Shiuan Chen, D. C. Rao, Depei Liu, James E. Hixson, L. Lee Hamm, C. Charles Gu, Paul K. Whelton, Jiang He, and for the GenSalt Collaborative Research Group
Arch Intern Med. 2008;168(16):1740-1746.
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