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Megan Barkell, PharmD

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Wysowski et al¹ reviewed the prevalence of bleeding complications associated with the use of warfarin sodium for the implementation of a "black box" warning and Medication Guide. These are not appropriate solutions to decrease bleeding adverse events. While the addition of black box warnings to package inserts can be a useful tool for many medications, the information contained in the warning for warfarin is considered general knowledge. It will not affect current practice.

Medication Guides are also an inefficient approach to increasing knowledge at the patient level. Medication Guides, on average, are written at an 11th- to 12th-grade reading level, which is not consistent with the Keystone recommendations of a sixth- to eighth-grade reading level.² Furthermore, only 23% of a population with low literacy skills reported attending to Medication Guides.³ These issues are concerning when 43% of adults in the United States have basic or below basic . . . [Full Text of this Article]

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RELATED LETTER

Bleeding Associated With Warfarin Use: Improving Outcomes—Reply
Diane K. Wysowski
Arch Intern Med. 2008;168(2):237.
EXTRACT | FULL TEXT  

RELATED ARTICLE

Bleeding Complications With Warfarin Use: A Prevalent Adverse Effect Resulting in Regulatory Action
Diane K. Wysowski, Parivash Nourjah, and Lynette Swartz
Arch Intern Med. 2007;167(13):1414-1419.
ABSTRACT | FULL TEXT