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  Vol. 168 No. 2, January 28, 2008 TABLE OF CONTENTS
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 •Revascularization
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COMMENTS AND OPINIONS
Are Thrombolytic Drugs Not Evidence-Based Medications?

Hans Van Brabandt, MD; France Vrijens, MSc

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We are not convinced that the results of the article by Labarere et al1 warrant the recommendation that patients with an acute myocardial infarction (AMI) should be admitted to a hospital with on-site percutaneous coronary intervention (PCI) facilities. In this observational study, there is an inequality in baseline characteristics of patients admitted to one or the other hospital. Most characteristics indicative for a worse prognosis were more prevalent in patients admitted to hospitals without on-site PCI. They were older and had more heart failure, more left bundle-branch block, and more chronic renal failure. This suggests a selection bias, favoring the admission of patients with a better prognosis to hospitals with on-site PCI. Although appropriate statistical methods have been used, it cannot be excluded that some unmeasured confounding factor (eg, severity of comorbid conditions and socioeconomic factors) may annihilate the adjusted residual difference in . . . [Full Text of this Article]


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RELATED ARTICLE

Outcomes of Myocardial Infarction in Hospitals With Percutaneous Coronary Intervention Facilities
Jose Labarere, Loic Belle, Magali Fourny, Nathalie Genès, Jean-Marc Lablanche, Didier Blanchard, Jean-Pierre Cambou, Nicolas Danchin, and for the Unité de Soins Intensifs Coronaires 2000 Investigators
Arch Intern Med. 2007;167(9):913-920.
ABSTRACT | FULL TEXT  






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