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COMMENTS AND OPINIONS
Thyroid Function and Body Weight: Should We Also Consider the Interplay With Insulin Resistance and Fat Distribution?
Alexis Elias Malavazos, MD;
Emanuele Cereda, MD;
Alessandra Delnevo, MD;
Elena Passeri, MD;
Antonietta Tufano, MD;
Laura Sburlati, MD;
Emanuela Orsi, MD;
Lelio Morricone, MD;
Bruno Ambrosi, MD
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We read with great interest the article "Relations of thyroid function to body weight" by Fox et al.1 As stated by the authors, some evidence suggests that modest increases in serum thyrotropin (TSH) concentration, within the reference range, may be associated with weight gain, but no causality can be inferred.1
On the basis of our experience, we would like to make some comments about this interesting issue. Overt thyroid dysfunction is well recognized to affect body weight, and this may have important clinical significance when obesity, as well as associated metabolic complications (eg, insulin resistance, chronic low-grade inflammation), are the undesirable counterparts. Along with this, the influence of obesity per se on thyroid function remains unclear, but recent observations suggest a relationship . . . [Full Text of this Article]
AUTHOR INFORMATION
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RELATED LETTER
Doctor . . . Could It Be My Thyroid?
Roy E. Weiss and Rebecca L. Brown
Arch Intern Med. 2008;168(6):568-569.
EXTRACT
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RELATED ARTICLE
Relations of Thyroid Function to Body Weight: Cross-sectional and Longitudinal Observations in a Community-Based Sample
Caroline S. Fox, Michael J. Pencina, Ralph B. D’Agostino, Joanne M. Murabito, Ellen W. Seely, Elizabeth N. Pearce, and Ramachandran S. Vasan
Arch Intern Med. 2008;168(6):587-592.
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