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Lawrence B. Cohen, MD

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

I read with interest the recently published article by Khurana et al¹ and would like to make several comments.

First, it is stated that OSP solution was the preferred bowel preparation. It would be helpful to know whether any patient in the study received OSP tablets and if so, how many? Second, the timing of the 2 doses is critical to the safety of this product. The Physicians' Desk Reference states that patients consuming OSP solution "should not exceed the recommended dosage (45 mL) in a 24-hour period,"² and an American Task Force concluded that dosing of aqueous OSP should be 45 mL x 2, separated by 10 to 12 hours. It would be helpful if the authors provided details on how OSP was dosed in this study.³ Third, fewer than 10% of all eligible patients qualified for study enrollment (286 of 3000), 95% of the . . . [Full Text of this Article]

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The Effect of Oral Sodium Phosphate Drug Products on Renal Function in Adults Undergoing Bowel Endoscopy
Anand Khurana, Luciana McLean, Sheree Atkinson, and Charles J. Foulks
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Oral Sodium Phosphate and Renal Function—Reply
Anand Khurana
Arch Intern Med. 2008;168(20):2286-2287.
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