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Doctor . . . Could It Be My Thyroid?
Roy E. Weiss, MD, PhD;
Rebecca L. Brown, MD
Arch Intern Med. 2008;168(6):568-569.
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Obesity is a result of net energy intake greater than energy expenditure. How many times have we told this to our patients and had them respond that, despite a vigorous commitment to a low-calorie diet and an exercise program, their weight continues to increase? Patients and investigators have long considered whether alterations in the hypothalamic-pituitary-thyroid (HPT) axis contribute to the energy equation such that low thyroid hormone levels result in obesity. Although thyroid hormone levels are frequently measured in the search for the holy grail of the overweight, the incidence of overt or subclinical hypothyroidism in subjects with obesity is relatively low.1 However, several studies have demonstrated that thyroid hormone levels, even within the reference range for the population, may be associated with obesity. A study of 4082 euthyroid Danes demonstrated a positive correlation between body mass index and serum thyrotropin . . . [Full Text of this Article]
AUTHOR INFORMATION
RELATED ARTICLE
Relations of Thyroid Function to Body Weight: Cross-sectional and Longitudinal Observations in a Community-Based Sample
Caroline S. Fox, Michael J. Pencina, Ralph B. D’Agostino, Joanne M. Murabito, Ellen W. Seely, Elizabeth N. Pearce, and Ramachandran S. Vasan
Arch Intern Med. 2008;168(6):587-592.
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