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David Z. J. Chu, MD

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Zahl et al¹ have presented very interesting findings in breast cancer rates among seemingly comparable groups of Norwegian women receiving multiple mammograms compared with a cohort receiving only 1 prevalence mammogram at the end of a 6-year study period. The 22% lower breast cancer rate in the control group was ascribed to spontaneous tumor regression. There are numerous other plausible explanations that the authors should investigate, which could lead to other interesting aspects of breast cancer screening and breast cancer epidemiology.

First, the women who chose not to undergo frequent screening probably considered themselves at lower risk for breast cancer development. Their family history of breast cancer is likely to be low in members affected. Their diet may differ, as well as their socioeconomic status. I would venture to guess that their socioeconomic status affects their location of residence, which may lead them to clinics . . . [Full Text of this Article]

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