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COMMENTS AND OPINIONS
Breast Cancer Overdiagnosis With Screening Mammography
Ismail Jatoi, MD, PhD;
William F. Anderson, MD, MPH
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The study by Zahl et al1 suggests that some of the occult invasive breast cancers detected by mammographic screening might ultimately have undergone spontaneous regression. Population-based statistics support this hypothesis as well.2 Indeed, since the advent of mammographic screening, age-specific breast cancer incidence rates in Europe have increased dramatically among women in those age groups targeted for screening.3 For example, in many Western European countries, systematic screening programs were introduced in the late 1980s and early 1990s for women aged 50 to 69 years, and this was followed by sharp increases in the incidence of invasive breast cancer in these women.3 This trend is also observed in the United States, as illustrated in the Figure, according to data from the Connecticut Historical database of the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) program. This Figure shows that, since . . . [Full Text of this Article] AUTHOR INFORMATION
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