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Katherine Esposito, MD, PhD; Dario Giugliano, MD, PhD

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We read with interest the article by Salas-Salvadó et al¹ describing the potential usefulness of a traditional Mediterranean diet enriched with nuts in the management of the metabolic syndrome (MetS). The effects of the interventional diets used in the study by Salas-Salvadó et al¹ are somewhat less than expected: according to a recent analysis, the 3 intervention studies that were specifically conceived to test the effect of dietary or lifestyle changes on the prevalence of MetS produced a weighed mean resolution rate of the syndrome of 25% (range, 20%-48%).² Interestingly enough, the intervention diets adopted in the 3 studies were similar to Mediterranean dietary patterns.

Why did the Spanish participants of the PREDIMED (Prevención con Dieta Mediterránea) Trial seem apparently more resistant to the effect of diet? First, the population was different: in the 3 studies,² participants had MetS or impaired glucose . . . [Full Text of this Article]

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RELATED ARTICLE

Effect of a Mediterranean Diet Supplemented With Nuts on Metabolic Syndrome Status: One-Year Results of the PREDIMED Randomized Trial
Jordi Salas-Salvadó, Joan Fernández-Ballart, Emilio Ros, Miguel-Angel Martínez-González, Montserrat Fitó, Ramon Estruch, Dolores Corella, Miquel Fiol, Enrique Gómez-Gracia, Fernando Arós, Gemma Flores, José Lapetra, Rosa Lamuela-Raventós, Valentina Ruiz-Gutiérrez, Mònica Bulló, Josep Basora, María-Isabel Covas, and for the PREDIMED Study Investigators
Arch Intern Med. 2008;168(22):2449-2458.
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Which Mediterranean Diet in the Management of Metabolic Syndrome?—Reply
Jordi Salas-Salvadó, Emilio Ros, Ramon Estruch, Maríia-Isabel Covas, and for the PREDIMED Study Investigators
Arch Intern Med. 2009;169(11):1077.
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