 |
|
COMMENTS AND OPINIONS
The Healthy Adherer Effect—Reply
Varda Shalev, MD;
Gabriel Chodick, PhD
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
In reply
We thank the authors of the letter for their comments. Andersohn and Willich noted some methodological concerns with our analysis, particularly the potential "healthy adherer" bias. A recent study1 aimed to examine whether adherence with statin use is associated with a decreased risk of unintentional injuries that were sought to be unrelated to statins (eg, motor vehicle crashes and workplace injuries, burns, and falls). As expected, they found a modest (10%-15%) overall reduction in the rate of unintentional injuries among adherent patients compared with nonadherent ones. Thus, the "healthy adherer" bias could explain some of our results, but clearly not a 45% reduction in all-cause mortality.
We agree with the authors that the reduction in all-cause mortality cannot be explained only by a decrease in cardiovascular diseases mortality, but probably by reducing mortality from other diseases due to the pleiotropic effects of . . . [Full Text of this Article]
AUTHOR INFORMATION
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
RELATED ARTICLE
Continuation of Statin Treatment and All-Cause Mortality: A Population-Based Cohort Study
Varda Shalev, Gabriel Chodick, Haim Silber, Ehud Kokia, Joseph Jan, and Anthony D. Heymann
Arch Intern Med. 2009;169(3):260-268.
ABSTRACT
| FULL TEXT
RELATED LETTER
The Healthy Adherer Effect
Frank Andersohn and Stefan N. Willich
Arch Intern Med. 2009;169(17):1635-1636.
EXTRACT
| FULL TEXT
|
