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Katrijn L. Rensing, MD; John J. P. Kastelein, MD, PhD; Marcel Twickler, MD, PhD

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We read with special interest the recent article by Kosiborod et al¹ in which they concluded that in hyperglycemic patients with acute myocardial infarction (AMI), glucose normalization after hospital admission is associated with better survival. They postulated that this effect on survival was independent of the administration of insulin. In addition, the authors suggested that lowering glucose levels with insulin therapy may be an option for future treatment strategies in hyperglycemic patients with AMI.

Looking at their interesting observations, we wonder whether insulin should be used as the preferable compound to lower glucose levels. From Figure 2 of their article,¹ the in-hospital mortality appeared to be more pronounced in patients who were treated with insulin (although not significant) compared with non–insulin-treated patients. This trend was present along almost all glucose level intervals. Therefore, these results might . . . [Full Text of this Article]

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