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William K. Hubbard, BA, MA

Arch Intern Med. 2009;169(18):1655-1656.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Contemporary Americans have little appreciation for the extent to which pharmaceuticals have changed the face of medicine in the past 75 years. Just think: before the advent of the "therapeutic revolution" that began with the development of penicillin in the 1930s, the physician's armamentarium of drug therapies was limited to aspirin, digoxin, and a handful of other effective treatments. Indeed, most commercial "medicines" of that era were so-called patent drugs, the active ingredient of which was alcohol—you didn't get well, but you felt better about it.

Since the US Food and Drug Administration's (FDA’s) drug review system was created in 1938, FDA scientists have approved over 3000 drugs. And that system has withstood the test of time. Most of those drugs remain on the market as safe and effective therapies. Today, virtually every disease has some effective drug treatment and many once-serious medical scourges have . . . [Full Text of this Article]

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