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  Vol. 172 No. 1, January 9, 2012 TABLE OF CONTENTS
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 •Bacterial Infections
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COMMENTS AND OPINIONS
Prophylaxis for Recurrent Urinary Tract Infections: Nitrofurantoin, Not Trimethoprim-Sulfamethoxazole or Cranberry Juice—Reply

Mariëlle A. J. Beerepoot, MD; Jan M. Prins, MD, PhD; Suzanne E. Geerlings, MD, PhD

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In reply

We appreciate the opportunity to respond to the letter from Dr Cunha. Two important issues are raised: episodic treatment vs prophylaxis for recurrent urinary tract infections (UTIs) and the choice of the antibiotic prophylaxis.

Effective prevention strategies for recurrent UTIs are particularly relevant for women at high risk for recurrence. In our study population the median recurrence rate in the year preceding inclusion was approximately 6 to 7 (mean number of symptomatic UTIs).1 In these women episodic treatment of recurrences instead of prevention causes significant discomfort and would have a high impact on ambulatory health care costs as a result of primary care and outpatient visits, diagnostic tests, and prescriptions.2 Continuous prophylaxis, postcoital prophylaxis with low-dose antibiotics, and intermittent self-treatment have all been demonstrated to be effective in managing recurrent UTIs in women.3 . . . [Full Text of this Article]


AUTHOR INFORMATION
Author Affiliations: Division of Infectious Disease, Department of Internal Medicine, Academic Medical Center, Amsterdam, Netherlands.



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RELATED LETTER

Prophylaxis for Recurrent Urinary Tract Infections: Nitrofurantoin, Not Trimethoprim-Sulfamethoxazole or Cranberry Juice
Burke A. Cunha
Arch Intern Med. 2012;172(1):82.
EXTRACT | FULL TEXT  






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