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New Weapon to Curb Smoking
No More Excuses to Delay Treatment
Arch Intern Med. 2006;166:1547-1550.
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Smoking is the leading cause of preventable death in the United States and worldwide.1 In the 20th century, smoking caused 100 million deaths. If present patterns persist, about 1 billion people will die from smoking-related diseases in this century. Finding efficacious treatments for nicotine dependence is an important health goal.2
Nicotine replacement therapy (NRT) is the mainstay of smoking cessation treatment. It includes chewing gum, skin patches, tablets, nasal spray, and inhalers and is designed to decrease withdrawal symptoms by replacing nicotine in the blood. All forms of NRT increase the likelihood that individuals will succeed in their smoking cessation attempts. The various types of NRT are equally efficacious, and additional counseling does not improve an individual's likelihood of success.3
Nevertheless, 3 major issues have promulgated scientific interest in the development of non-NRT pharmacotherapies for the treatment of nicotine dependence. First, although various forms of NRT can nearly double the . . . [Full Text of this Article] AUTHOR INFORMATION
Bankole A. Johnson, DSc, MD, PhD
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