• Online Features  This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (11)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Men's Health  • Men's Health, Other  • Neurology  • Stroke  • Occupational and Environmental Medicine  • Alert me on articles by topic  Social Bookmarking   What's this?

Akizumi Tsutsumi, MD; Kazunori Kayaba, MD; Kazuomi Kario, MD; Shizukiyo Ishikawa, MD

Arch Intern Med. 2009;169(1):56-61.

Background  No prospective studies have examined the association between occupational stress according to the job demand–control model and the risk of stroke in Asian populations.

Methods  We conducted a multicenter community-based prospective study of 6553 Japanese male and female workers. Occupational stress was evaluated using a Japanese version of the job demand–control model questionnaire. We used the Cox proportional hazards model to evaluate the association between occupational stress and stroke.

Results  During a mean follow-up of 11 years, we identified 147 incident strokes. Multivariable analysis revealed a more than 2-fold increase in the risk of total stroke among men with job strain (combination of high job demand and low job control) (hazard ratio, 2.73; 95% confidence interval, 1.17-6.38) compared with counterpart men with low strain (combination of low job demand and high job control) after adjustment for age, educational attainment, occupation, smoking status, alcohol consumption, physical activity, and study area. Additional adjustments for biologic risk factors attenuated the hazard ratio, but there continued to be statistical significance (hazard ratio, 2.53; 95% confidence interval, 1.08-5.94). In women, no statistically significant differences were found for any stroke incidence among the job characteristic categories.

Conclusion  Occupational stress related to job strain was associated with incident strokes among Japanese men.

Author Affiliations: Division of Health Care and Promotion, Occupational Health Training Center, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan (Dr Tsutsumi); Department of Health and Social Services, Saitama Prefectural University, Koshigaya, Saitama, Japan (Dr Kayaba); and Division of Cardiovascular Medicine, Department of Medicine (Dr Kario), and Division of Community and Family Medicine (Dr Ishikawa), Jichi Medical University School of Medicine, Tochigi, Japan.

CiteULike    Connotea    Delicious    Digg    Facebook    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

A prospective study of work stressors and the common cold
Park et al.
Occup Med (Lond) 2011;61:53-56.
ABSTRACT | FULL TEXT