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Treatment of Chronic Bronchitis and Bronchiectasis with Intravenous TetracyclineResults, as Judged by Studies of the Sputum and Tests of Pulmonary Function
RONALD E. FOX, M.D.;
HARRY F. DOWLING, M.D.;
GEORGE A. SAXTON, Jr., M.D.;
MARGARET MELLODY, M.S.
AMA Arch Intern Med. 1957;100(1):11-17.
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Antibiotics have been successful in controlling many of the cases of pneumonia that occur in patients with chronic bronchitis or bronchiectasis, but their effect upon the underlying disease is uncertain. Analysis of the problem is complicated by uncertainty as to which of the many micro-organisms that are cultured from the sputum of patients with bronchiectasis are etiologic and which are merely saprophytes. Mulder and his associates 1-3 and many other investigators 4-8 stressed the importance of Hemophilus influenzae in chronic bronchitis and bronchiectasis. Pneumococci appear to be the next most frequent pathogenic organisms, although the frequency with which they are cultured depends upon the thoroughness of the search. Stuart-Harris et al.7 cultivated them from 58% of sputa from patients with bronchiectasis and 51% of sputa from patients with chronic bronchitis. Allison and his associates 4 found them in only 11% of their patients with bronchiectasis. May8 cultured them
. . . [Full Text PDF of this Article]
Author Affiliations
Chicago
From the Research and Educational Hospitals, University of Illinois, and the Departments of Medicine and Preventive Medicine, University of Illinois College of Medicine.
Footnotes
Submitted for publication Nov. 16, 1956.
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