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Essential Fatty Acids and AtherosclerosisA Critique of the Present Knowledge
GEORGE V. MANN, Sc.D., M.D.
AMA Arch Intern Med. 1957;100(1):77-84.
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Recent publications from the University of Capetown, South Africa, by Bronte-Stewart and his colleagues 1,2 have led to wide interest and discussion among nutritionists and chemists concerned with atherogenesis because a new lead to the problem seems to have been created. The work of the South African group has appeared to many as a de novo stroke of brilliant insight and experimentation which promises to redirect further research in atherosclerosis. Furthermore, the urgency of the clinical problems which result from atherosclerosis has lead with startling rapidity to the dissemination among clinicians of "practical methods" for influencing the atherosclerotic process.3 It is worth reviewing the history of these developments in order to find the origin of the concepts and a fair estimate of the meaning of the data and, finally, to evaluate the justification for submitting patients to regimens based on this evidence.
The fundamental working hypothesis for much of
. . . [Full Text PDF of this Article]
Author Affiliations
Wellesley Hills, Mass.
From the Heart Disease Epidemiology Study, of the National Heart Institute, Framingham, Mass.
Footnotes
Submitted for publication Feb. 5, 1957.
This material has been adapted from a review of the subject which was prepared in July, 1956, for the use of the National Heart Council, Bethesda, Md. The opinions expressed represent the author's and are not necessarily those of the Heart Council.
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