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Alcohol-Induced Pain as a Manifestation of Hodgkin's DiseaseAn Investigation of Its Specificity and Frequency
The Medical Resident Staff of the Grace-New Haven Community Hospital (1955-1956);
Harold O. Conn, M.D.
AMA Arch Intern Med. 1957;100(2):241-247.
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Attention has recently been directed to the observation that some patients with Hodgkin's disease experience pain following the ingestion of alcohol. Hoster, who recorded this symptom in 1950, emphasized that the pain occurred immediately after the ingestion of small amounts of alcoholic beverages.1 Other authors have described this symptom in 27 additional patients.2-12 These reports, with a few exceptions,6,8,10 were based upon the patients' histories, without objective confirmation of the symptom. Analysis of these cases reveals that the pain may occur at the site of an osseous or lymphatic lesion anywhere in the body. It may be so severe that alcohol ingestion is carefully avoided. A wide variety of wines, beers, whiskies, and mixed drinks has been implicated, indicating that ethanol is the ingredient responsible for the pain. This is substantiated by the fact that intravenously administered ethyl alcohol caused pain in one patient.11 The pain
. . . [Full Text PDF of this Article]
Author Affiliations
Senior Resident, New Haven, Conn.
Instructor in Medicine, Yale University School of Medicine (Dr. Conn.).
Footnotes
Submitted for publication Jan. 31, 1957.
The members of the medical resident staff are as follows: G. A. Belkin, M.D.; I. M. Braverman, M.D.; J. T. Carpenter Jr., M.D.; R. G. Crounse, M.D.; D. S. Dock, M.D.; J. E. Dooley, M.D.; J. P. Dunn, M.D.; F. R. Fekety Jr., M.D.; W. L. Floyd, M.D.; G. M. Goza Jr., M.D.; L. H. Grant, M.D.; A. Huvos, M.D.; D. M Levy, M.D.; J. S. McGuire Jr., M.D.; J. M. Moses, M.D.; P. F. Mullinax Jr., M.D.; J. P. Nolan Jr., M.D.; L. M. Schiffer, M.D.; W. Y. Trotter, M.D., and R. I. Weed, M.D.
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