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SIDNEY RUBENFELD, M.D.; S. STEVEN BRODIE, Ph.D.; NATHAN MITCHELL, M.D.; MARTIN LOWENTHAL, M.D.; ANTHONY KOHN, M.D.

AMA Arch Intern Med. 1957;100(2):266-271.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The 24-hour uptake of I¹³¹ by the thyroid gland does not always reflect the true clinical picture of thyroid disease. Hence, additional confirmatory tests were introduced in order to clarify the discrepancies. This presentation correlates the 24-hour I¹³¹ uptake, salivary tests, and conversion ratios with the clinical status of a group of euthyroid, hyperthyroid, and hypothyroid patients diagnosed by history, physical examination, and other laboratory procedures.

Methods

This study included 164 patients referred for thyroid evaluation. Each patient was thoroughly investigated clinically. None of the patients had any previous radioiodine therapy. The 24-hour I¹³¹ uptake, conversion ratio, and salivary count were done 24 hours after the oral administration of about 50µc of I¹³¹ in 25 cc. of tap water.

The tracer doses of I were accurately measured in terms of microcuries, using a modified Braestrup ionization chamber and linear electrometer circuit calibrated with a 20 U. S. . . . [Full Text PDF of this Article]

Author Affiliations
New York

From the Radio-Isotope Service of Jewish Memorial Hospital.

Footnotes
Accepted for publication March 12, 1957.

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