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Acute Renal Failure Due to Scleroderma Kidney DiseaseA Report of One Case with Autopsy Findings
HERBERT L. FRED, M.D.;
OSCAR N. RAMBO, M.D.
AMA Arch Intern Med. 1957;100(5):813-818.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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The appearance of characteristic renal lesions with marked impairment of renal function is not uncommon in periarteritis nodosa and systemic lupus erythematosus.1-6 However, in another collagen disorder, scleroderma, the occurrence of a characteristic kidney lesion together with fatal renal insufficiency is not generally recognized and has been reported only recently.7 The following case illustrates that renal dysfunction may be the only clinical manifestation of visceral scleroderma and that death may result therefrom.
Report of Case
First Admission (April 6 to April 28, 1954).
— A 39-year-old white male mechanic supervisor was referred to the hospital for treatment of scleroderma.
About two years prior to admission he developed generalized myalgia associated with painful, swollen, and numb joints of the hands and feet. Tightness of the skin over the hands, feet, and face appeared and was accompanied by inability to close the hands completely or to open the mouth normally.
. . . [Full Text PDF of this Article]
Author Affiliations
Salt Lake City
Trainee, National Institute of Arthritis and Metabolic Diseases, National Institutes of Health (Dr. Fred); from the Departments of Medicine and Pathology, University of Utah College of Medicine and the U. S. Veterans' Administration Hospital (Dr. Rambo).
Footnotes
Submitted for publication April 23, 1957.
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