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WILLIAM H. PERLOFF, M.D.; HARRY E. HADD, M.A.; BERTRAM J. CHANNICK, M.D.; JOHN H. NODINE, M.D.

AMA Arch Intern Med. 1957;100(6):981-985.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the unfortunate woman afflicted with hirsutism, excessive facial and/or body hair represents a serious aesthetic and psychological problem; to her physician, it often presents a frustrating dilemma in diagnosis and management. Usually benign, it may be the sole manifestation of a serious underlying endocrine disorder. Hirsutism has been noted in children with hypothalamic lesions,¹ congenital ectodermal dysplasia,² hypothyroidism,³ polyostotic fibrous dysplasia,⁴ inanition and wasting, and under body casts worn for long periods of time. The starvation state, also called "the hibernation syndrome," is also associated with hirsutism in adult females; the reason for excessive hair growth is unknown. Pituitary gland tumors are found occasionally in women with signs of virilization including hirsutism; in most instances manifest adrenocortical hyperplasia is present, suggesting mediation through the adrenals.

Hyperplasia or tumor of the adrenal cortex leads to one or a variable combination of two syndromes. If the abnormality . . . [Full Text PDF of this Article]

Author Affiliations
Philadelphia

From the Department of Endocrinology, Temple University School of Medicine and Medical Center. Associate Professor of Medicine and Director of the Department of Endocrinology (Dr. Perloff); Instructor in Endocrinology and Endocrine Chemist (Mr. Hadd), and Instructors in Medicine (Drs. Channick and Nodine).

Footnotes
Submitted for publication May 20, 1957.

Aided by a Grant from Schering Corporation, Bloomfield, N. J.

Read before the Section on Internal Medicine at the 106th Annual Meeting of the American Medical Association, New York, June 5, 1957.

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