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CAPT. GERALD WEISSMANN, MC

AMA Arch Intern Med. 1958;101(1):108-113.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Osteopoikilosis, also called "osteopecilia" or "spotted bone disease," is a rare condition of bone, manifest by multiple small islands of dense bone formation in areas where normally cancellous bone is found. Ritvo¹ states that these lesions "vary in size from 2-3 mm. to 3 cm. occurring frequently in the epiphysis and adjacent parts of the metaphysis, usually being more numerous in the latter. The areas of density lie in the cancellous bone, and, as a rule, are entirely free from the cortex. Patients have been observed over a number of years with no apparent change in the roentgen manifestations." While the apparently hereditary, and essentially benign, course of the disease is stressed in most reports,^2-6 a considerable amount of literature has accumulated concerning associated conditions.^7-11 Two types, distinguished roentgenologically, are described: linear and millet-like.

Most of these associated defects are related to skeletal and cutaneous lesions. The . . . [Full Text PDF of this Article]

Author Affiliations
U. S. Army

From the Medical Service of the United States Army Hospital, Fort Dix, N. J. Assistant Resident in Medicine, the Mount Sinai Hospital, New York.

Footnotes
Submitted for publication April 23, 1957.

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