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PHILIP F. WAGLEY, M.D.; JOHN A. RUMSFELD, M.D.

AMA Arch Intern Med. 1958;101(2):300-305.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The purpose of this report is threefold. Firstly, these data reemphasize the chronicity of the disorder, paroxysmal nocturnal hemoglobinuria (PNH). Secondly, this case illustrates a clinical recovery with the persistence of the underlying erythrocyte abnormality. Thirdly, and most important, it demonstrates that routine hematological studies may fail to suggest the presence of this entity. Therefore, it seems logical to suspect that this condition is commoner than generally considered. At the time this case was first studied and published,¹ there had been one other reported in the American literature.² As the fundamental and meticulous work on this disorder by Ham³ and Ham and Dingle⁴ in the Thorndike Memorial Laboratory marked an early phase of many years of careful and original observations on the mechanisms of red blood cell destruction by Dr. W. B. Castle* and those who have had the privilege of associating with him,^5-11 it . . . [Full Text PDF of this Article]

Author Affiliations
Baltimore

Footnotes
Submitted for publication Sept. 30, 1957.

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