This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Observations on the Immune Disturbance

NORMAN M. KAPLAN, M.D.; ABRAHAM I. BRAUDE, M.D.

AMA Arch Intern Med. 1958;101(3):515-523.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The immunity of adults to certain common infections of childhood can usually be related to the acquisition of specific antibody through contact with micro-organisms. Immunity to infection by Hemophilus influenzae, Type B, is an excellent example of the solid and durable resistance acquired against a childhood infection and maintained by repeated exposure to the bacillus. The low rate of adult infection is illustrated by the fact that in 467 cases of H. influenzae meningitis only 15 were in patients over the age of 20.^1-5 An extensive review of the literature has disclosed among adults only 33 cases of meningitis ^5-10 and scattered reports of endocarditis, brain abscess, obstructive laryngitis, pyarthrosis,¹¹ and pneumonia¹² due to H. influenzae, Type B.

While the resistance of most adults to infection by H. influenzae is readily understood on the basis of acquired immunity, little effort has been made to explain the lack . . . [Full Text PDF of this Article]

Author Affiliations
Dallas, Texas; Pittsburgh

From the Department of Internal Medicine, Southwestern Medical School of the University of Texas, Dallas, Texas.

Footnotes
Submitted for publication Aug. 1, 1957.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?