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  Vol. 101 No. 4, APRIL 1958 TABLE OF CONTENTS
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The Analgesic Properties and Addiction Liability of Ketobemidone and Morphine

PENTTI PELTOLA, M.D.; PAUL SOISALO, M.D.

AMA Arch Intern Med. 1958;101(4):741-746.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Many papers dealing with the clinical use of ketobemidone (Cliradon, Ciba) have called attention to the low potentiality for addiction of this drug. Studies based on large series of cases have shown that patients can give up its use without particular difficulty (Lewis, 1949; Cecchi, 1950; Blanke, 1950; Liessem, 1951; Peltola, 1952). Thus, in spite of fairly extensive use, comparatively few cases of addiction to ketobemidone have been brought to notice. Only in Germany, where the sale of the drug was unrestricted until 1953, has there been a significant number of addicts. There are reports on 20 cases in Germany either of addiction or of misuse (Linder and Vollmar, 1950; Bernmeier and Heine, 1950; Sattes, 1951; Kinzler, 1952; Mühlau, 1952; Cieslak, 1952; Hamburger, 1952; Geller, 1952; Carrière, 1953) and on 4 cases in other parts of the world (Bernstein, 1949; Del Bono, 1952; Peltola, 1952). We may assume, however, that . . . [Full Text PDF of this Article]


Author Affiliations

Helsinki, Finland

From the Medical Department of the Kivelä Hospital.


Footnotes

Submitted for publication March 12, 1957.



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