This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

VINCENT P. DOLE, M.D.

AMA Arch Intern Med. 1958;101(5):1005-1008.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Recent studies have clarified some aspects of fatty acid transport. The results promise to be of clinical importance, since fat, as a major energy source and as a component of body structure, plays a central role in chronic diseases of metabolism. For example, obesity can be conceived as an abnormal balance between the total amount of fatty acid stored in adipose tissue and its availability as substrate for working cells. Arteriosclerosis is characterized by abnormal deposits of fatty acid esters. Diabetes, although usually defined by high blood sugar, is in fact a general disturbance of metabolism, and its most dangerous complications can be traced to faulty handling of fatty acids.

During the past few years a number of laboratories, including ours, have been studying a fatty acid fraction which is remarkable for both its speed of turnover and its close relation to the state of carbohydrate metabolism. This fraction, the . . . [Full Text PDF of this Article]

Author Affiliations
New York

Rockefeller Institute for Medical Research.

Footnotes
Submitted for publication Dec. 31, 1957.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?