This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (11)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

ROGER M. DES PREZ, M.D.; AVRUM ORGANICK, M.D.

AMA Arch Intern Med. 1958;101(6):1129-1142.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Hope of benefit from the use of corticotropin and corticosteroid in various types of bacterial infections is based on three assumptions: first, that some reactions to infections may be themselves quite harmful to the host; second, that these hormones in some poorly understood way alter or suppress host responses to infection; third, that the available antimicrobial agents are capable of controlling the infection in a host which has been so altered.

The costly aspects of some host reactions to tuberculous infection are well known. In acute wide-spread pulmonary tuberculosis the marked toxicity and at times impaired respiratory function may result in early fatality before the full effects of chemotherapy have developed. (Four cases thought to be in this category are the basis of this report.) In chronic stages replacement of parenchyma by fibrosis implies some permanent functional impairment. Caseation necrosis is locally bacteriostatic,¹ but it also may lead . . . [Full Text PDF of this Article]

Author Affiliations
Fort Defiance, Ariz.

From the Department of Medicine, The New York Hospital-Cornell University Medical College. Resident Fellow of the American Trudeau Society (Dr. Des Prez).

Footnotes
Submitted for publication Oct. 23, 1957.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?