This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on Web of Science (8)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

EDWIN F. HIRSCH, M.D.

AMA Arch Intern Med. 1958;102(6):1024-1035.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Atherosclerosis of the aorta and of its main arterial branches ranks high among the causes of natural death in man. Although the records and observations of atherosclerosis in man and in lower animals extend far into antiquity, no generally accepted cause for the evolution of the disease has been proposed. Opinions expressed recently^4,5 offer the hypothesis that diets rich in animal fats have a causal relation to atherosclerosis in man. The implied impact of this fat-rich diet on the arterial tissues is through the lipids in transport in the blood and from which the lipids in the fatty plaques of the intima are derived.

Some regard the lesions of atherosclerosis as part of an aging process; others think that they are caused by lipid infiltrations of the intima and result from disorders of lipid metabolism.² Each view alone is confronted with pertinent objections. The one view emphasizes a . . . [Full Text PDF of this Article]

Author Affiliations
Chicago

From the Henry Baird Favill Laboratory of Presbyterian-St. Luke's Hospital.

Footnotes
Submitted for publication June 25, 1958.

Chairman's Address, read before the Section on Pathology and Physiology at the 107th Annual Meeting of the American Medical Association, San Francisco, June 25, 1958.

The Seymour Coman Fellows of the Departments of Chemistry and of Pathology of The University of Chicago have made significant contributions to the studies of atherosclerosis herein reviewed.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?