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W. M. MIKKELSEN, M.D.; I. F. DUFF, M.D.; C. W. CASTOR, M.D.; H. A. ZEVELY, M.D.; A. J. FRENCH, M.D.

AMA Arch Intern Med. 1958;102(6):977-985.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The technique of biopsy occupies a position of undisputed importance as a diagnostic procedure. It has not found wide application in the field of rheumatic diseases, however, because of the expense and period of incapacity involved with conventional arthrotomy. The situation was significantly improved, we believe, in 1951, when Polley and Bickel¹ described their experiences with an instrument for punch biopsy of the synovial membrane. In several subsequent reports^2-4 these authors have confirmed their opinion regarding the diagnostic value of the method. Our initial report ⁵ was in agreement, stating that the procedure was considered a practical diagnostic method.

The Polley-Bickel instrument (Fig. 1) is simply constructed. The main part is a hollow stainless-steel tube with a trocar point and a hooked opening on the dorsal surface near the trocar tip. A hollow tubular knife with a sharp cutting rim fits inside the outer tube and is used . . . [Full Text PDF of this Article]

Author Affiliations
Ann Arbor, Mich.

Footnotes
Submitted for publication Aug. 8, 1958.

Read before the Section on Internal Medicine at the 107th Annual Meeting of the American Medical Association, San Francisco, June 25, 1958.

From the Rackham Arthritis Research Unit and the Department of Pathology, University of Michigan. The Rackham Arthritis Research Unit is supported by a grant from the Horace H. Rackham School of Graduate Studies. The expenses of this study were defrayed in part by grants from the Michigan Chapter, Arthritis and Rheumatism Foundation, and a grant from the United States Public Health Service.

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