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II. Medical Aspects of Delayed Convalescence

LEIGHTON E. CLUFF, M.D.; ROBERT W. TREVER, M.D.; JOHN B. IMBODEN, M.D.; ARTHUR CANTER, Ph.D.

AMA Arch Intern Med. 1959;103(3):398-405.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Four clinical types of brucellosis were described by Hughes in his classical monograph on "Mediterranean, Malta, or Undulant Fever." ¹ These were characterized as malignant, undulatory, mild or intermittent, and irregular or mixed, depending largely upon the severity, duration, and course of the infection. Although brucellosis, as studied by Hughes, was probably due almost exclusively to Brucella melitensis, his classification and description of the disease became widely accepted regardless of the species of Brucella causing infection. Cases were included in Hughes' studies only if the evidence was sufficient to "prove" the diagnosis. Hughes' classification of brucellosis has been criticized in that he did not describe cases of chronic disability.² Bassett-Smith, in 1903,³ however, described patients with "chronic brucellosis" who had persistent ill health, with fatigability and inability to carry on normal activities even in the face of a declining or negative agglutinin titer and without physical abnormalities. Acute . . . [Full Text PDF of this Article]

Author Affiliations
Baltimore

From the Departments of Medicine and Psychiatry, The Johns Hopkins University School of Medicine, and The Johns Hopkins Hospital. Markle Scholar in the Medical Sciences (Dr. Cluff).

Footnotes
Submitted for publication June 17, 1958.

This work supported by Contract No. DA-18-064-404-CML-100 with the Army Chemical Corps, Fort Detrick, Frederick, Md.

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