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The Management of Parkinson's Disease
ALBERT C. ENGLAND, Jr., M.D.;
ROBERT S. SCHWAB, M.D.
AMA Arch Intern Med. 1959;104(3):439-468.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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I. Historical Review
In 1817, James Parkinson 1 described six cases of the condition which now bears his name. These were all men with a disease state he characterized by tremor, loss of finger and arm dexterity, propulsion, festination and falling, insomnia, constipation, and dorsal kyphosis. Finally, there came on aphonia, dysphagia, and incontinence. From reading the text, it is apparent that these cases had generalized slowness of movement and marked dependence on others for the ordinary tasks such as eating, dressing, and walking. Rigidity is curiously not mentioned, but it is fair to say that it must have been present in order that the other symptoms might appear. The following quotation will remind present-day students of the acuity of his observations:
.... [p. 3] The first symptoms perceived are, a slight sense of weakness with a proneness to trembling in some particular part; sometimes in the head but most commonly
. . . [Full Text PDF of this Article]
Author Affiliations
Boston
From the Department of Neurology of the Harvard Medical School and the Neurological Service and Parkinson Clinic of the Massachusetts General Hospital. Instructor in Neurology, Harvard Medical School, and Associate in Parkinson Research Program, Massachusetts General Hospital (Dr. England); Assistant Clinical Professor of Neurology, Harvard Medical School, Neurologist and Director of Parkinson Research Program, Massachusetts General Hospital (Dr. Schwab).
Footnotes
Submitted for publication April 9, 1959.
Supported in part by the Allen P. and Josephine B. Green Foundation, Mexico, Mo., and the Parkinson's Disease Foundation, Inc., New York.
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