This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (6)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A Challenge to the Internist

DWIGHT C. ENSIGN, M.D.; JOHN W. SIGLER, M.D.; G. M. WILSON, Jr., M.D.

AMA Arch Intern Med. 1959;104(6):949-958.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The remarkable suppressive effect of adrenocortical steroids on symptoms of rheumatoid arthritis has led many patients and physicians to rely solely on these preparations. This course, fraught with dangers, is in many instances more threatening than the disease itself. Some of these hazards were recognized in the preliminary report of Hench and associates.¹ Two brief quotations from their original contribution seem especially pertinent after the interval of 10 years. "The rarity of these compounds presently and in the immediate future, and the limited scope of our preliminary data (especially regarding prolonged administration) make inappropriate now the use of the term 'treatment' except in an investigative sense. This paper is presented, not as a clinicotherapeutic report, but as a study of certain physiologic effects which these new hormones exert on rheumatoid arthritis.... Much more experience is needed before we shall know how effective or safe the prolonged administration of Compound . . . [Full Text PDF of this Article]

Author Affiliations
Detroit

Division of Arthritis, Henry Ford Hospital.

Footnotes
Received for publication June 23, 1959.

Read before the Section on Internal Medicine at the 108th Annual Meeting of the American Medical Association, Atlantic City, June 9, 1959.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?