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  Vol. 105 No. 2, FEBRUARY 1960 TABLE OF CONTENTS
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A Study of Etiologic Factors in So-Called Primary Pulmonary Hypertension

ARNOLD J. RAWSON, M.D.; HARRY M. WOSKE, M.D.

AMA Arch Intern Med. 1960;105(2):233-243.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Primary pulmonary hypertension (PPH) has been aptly defined by Evans 1 as hypertension of the lesser circulation in the absence of heart disease (other than cor pulmonale), parenchymal lung disease, or vascular disease of known etiology involving the pulmonary arterial tree. The histologic appearance of the lungs in recorded cases of primary pulmonary hypertension suggests that this designation includes more than one disease entity.

We have had the opportunity to study, clinically and at autopsy, four examples of PPH. On the basis of the histologic appearance of the lungs these cases appeared to form a well-defined group, suggestive of a single disease entity. Clinically and pathologically there was also noted an unusually high incidence of certain features which apparently were not the result of pulmonary hypertension. These were Raynaud's phenomena, arthritis, certain lesions suggestive of "collagen" disease, and similar symptoms in close relatives (Table 1).

The above findings prompted . . . [Full Text PDF of this Article]


Author Affiliations

Philadelphia

From the Departments of Pathology and Medicine, University of Pennsylvania School of Medicine. Dr. Rawson is Assistant Professor of Pathology.


Footnotes

Submitted for publication July 8, 1959.

Present address of Dr. Woske is Media Clinic, Media, Pa.



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